Abstract

A STUDY ON SYNTHESIS OF SILVER NANOPARTICLES AND ANTIBACTERIAL ACTIVITY OF ACALYPHA HISPIDA

Sasikumar J.*, Mahendran K., Nadanakumar K., Ramesh Babu N. G. and Saravanan N.

ABSTRACT

Most of the medicinal plants have antibacterial activity since they are rich in phytochemicals that possess drug producing properties. The current study carried out to perform the phytochemical analysis, antibacterial and silver synthesizing properties of Acalypha hispida. The leaves of the Acalypha hispida was collected, dried and treated with methanol and the methanol extract has been used for the above mentioned studies. The higher concentrations of methanol extract of Acalypha hispida inhibited the activities of microbes such as K. pneumonia, P. aeruginosa, E. coli, S. typhi. The phytochemical analysis of the methanol extract revealed that the plant has major phytochemicals except saponin, oils and resins and arthroquinone. It was also demonstrated that the plant (methanol extract) exhibits anti -bacterial activity and was determined by radial immunodiffusion techniques. The extract also has reducing capacity and reduced the silver nitrate solution to silver nanoparticles (AgNPs). Silver nanoparticles are characterized by UV-Visible spectroscopy, FTIR and confirmed by SEM analysis. Silver nanoparticles play an important role in immunity development.

Keywords: Acalypha hispida, Phytochemical analysis, Silver nanoparticles (AgNPs), Antibacterial activity.