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REVIEW: THE IN-VIVO SCREENING METHODS OF ANTICANCER DRUG
Shirish Patil*, Sudhir Patil, Nitin Kokare and Akshata Pujari
ABSTRACT
Cancer is one of the major life threatening diseases in the world. The available anticancer drugs have distinct mechanisms of action which shows varying effects on different types of normal and cancer cells. Screening methods are routinely and extensively used as concerned with cost and time reduction in drug discovery. The traditional anticancer drug screening methods, including animal experiments and cell-based screening assays. The screening and evaluation procedures for the development of anticancer agents indicated that the entire process which is a difficult task. Presently, active compounds are selected by prescreening and screening against transplanted mouse Keywords: Cancer, tumor xenografts, chemotherapy. [Download Article] [Download Certifiate] |