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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

DETECTION THE ROLE OF SOME INFLAMMATORY MARKERS IN PATIENT WITH ACUTE AND CHRONIC TONSILLITIS

Aysha W. Abd ALaziz*, Sahlah K. H. Abbas and Salah S. Zain Alabedin

ABSTRACT

This study was designed to evaluate the hematological and some immunological parameters in patients with acute and chronic tonsillitis. swabs were obtained from the tonsils of 100 patients with acute and chronic tonsillitis to detect streptococcus pyogenes and staphylococcus aureus. and blood samples collected to detect the immune parameters in the patient's serum. The results of culture showed that 18 samples (11.92%) were positive to strep. pyogenes while 29 samples (19.21%) were positive to staph. Aureus. A complete blood count showed statistically significant changes in the presence of tonsillitis. Serological test showed significantly increased in the complement protein C3, C4 and IgA level In acute and chronic tonsillitis. Serum level of IL-10 and TNF-α showed statistically difference due to its multiple functions, including cellular regulatory function and influence in many diseases, including tonsillitis.

Keywords: Acute tonsillitis, Chronic tonsillitis, IL-10, TNF- ?, Complement, IgA.

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