Abstract

EVALUATION OF ANTIULCER ACTIVITY OF ASPARAGUS RACEMOSUS ON EXPERIMENTAL ANIMALS

Madhuri M. Dhengale*, Jugal V. Vyas, Vishal R. Rasve and Chanda M. Thote

ABSTRACT

In present, peptic ulcer is a worldwide problem and its prevalence is quite high in India. Some present data shows that in different part of India its occurrence is 4 to 10% per thousand populations. The exact etiology of peptic ulcer is not known, the disease results in chronic suffering, loss of working hours and occasional fatality. The life time prevalence of peptic ulcer disease (PUD) in United States is approximately 12% in men and 10% in women. In USA, approximately 4 million individuals have peptic ulcers, while each year about 350,000 new cases are diagnosed; about 100,000 patients are hospitalized and at least about 3000 people die as a result of the disease. Smoking habit, alcoholism, stress & spicy food make the severity of the disease which leads serious complication of ulcer. Asparagus Racemosus is one of the most commonly use in different medical conditions has been documented. Traditionally, Asparagus Racemosus are beneficial in the treatment of diseases related to lungs & airways, blood, skin, stomach, intestines, and liver. As no reports are available on the possible antiulcer effects of Asparagus Racemosus. The present work was carried out to antiulcer activity of Asparagus Racemosus by ethanol induced gastric ulcers in wister albino Test drug Asparagus Racemosus (low dose) and Asparagus Racemosus (high dose) have shown result in comparison to standard drug omeparazole and control drug. Thus study has provided documentary evidence for antiulcer property of Asparagus Racemosus for its activity.

Keywords: Asparagus Racemosus, Shatavari, Peptic Ulcer, Ulcer Score, Asparagaceae, Omeprazole.