Abstract

THE DRUG TARGETING IN ALZHEIMER’S OR APPLICATIONS & ITS HAZARDS

Unama Yezdani, Mohd. Gayoor Khan*, Fazal Khan, Arvind Verma, Nilesh Kushwah, Rohit Verma

ABSTRACT

From The era's is the most common from of dementia that is characterised by a progressive decline in cognitive function in brains of Alzheimer’s patients. The massive injury and death of neutrons the brain involved In learning and loss of memory called the hippocampus or the spreads to other areas. The although there remains some uncertainty about the mechanism behind disease. Nano technology is advanced form of drug targeting is designed basically for treathment of diseases with the help of nano-particles because they target particular site for an action .The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy and many more also help in Alzheimer’s therapy etc. Interestingly pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs and up to recently did not realize that carrier systems themselves may impose risks to the patient. The kind of hazards that are introduced by using nanoparticles for drug delivery are beyond that posed by conventional hazards imposed by chemicals in classical delivery matrices etc.

Keywords: drug delivery, Alzheimer's therapy, nanoparticles, toxicology, pharmaceuticals etc.