Abstract

A REVIEW ON NATURAL BIOACTIVE COMPOUNDS AS POTENTIAL ANTI-WRINKLE AGENTS

Sk. Asma Shaheda*, Duraivel S, Niharika. R, P. Anusha, Sayyed Meharaj Qudusiya

ABSTRACT

Anti-aging creams are predominantly moisturiser-based cosmeceutical skin care products marketed with the promise of making the consumer look younger by reducing, masking or preventing signs of skin aging. These signs are laxity (sagging), rhytids (wrinkles) and photoaging, which includes erythema (redness), dyspigmentation (brown discolorations), solar elastosis (yellowing), keratoses (abnormal growths) and poor texture. Anti-aging creams may also focus on specific causes of skin aging, such as exposure to the sun. Despite great demand, many anti-aging products and treatments have not been proven to give lasting or major positive effects. The best performing creams reduce wrinkles by less than 10% over 12 weeks, which is not noticeable to the human eye. Skin aging involves degradation of extracellular matrix (ECM) in both the epidermal and dermal layers, it leaves visible signs on the surface of skin and the physical properties of the skin are modified. Chronological aging is due to passage of time, whereas premature aging occurred due to some environmental factors on skin produces visible signs such as irregular dryness, dark/light pigmentation, sallowness, severe atrophy, telangiectases, premalignant lesions, laxity, leathery appearance and deep wrinkling. Ample varieties of phytomolecules such as aloin, ginsenoside, curcumin, epicatechin, asiaticoside, ziyuglycoside I, magnolol, gallic acid, hydroxychavicol, hydroxycinnamic acids, hydroxybenzoic acids, etc. scavenges free radicals from skin cells, prevent trans-epidermal water loss, include a sun protection factor (SPF) contribute to protect skin from wrinkles, leading to glowing and healthy younger skin. The plants from traditional and other resources need to be evaluated based on the combined approaches of exploitation and exploration to find effective leads from natural resources useful in the treatment of skin wrinkling

Keywords: Wrinkles, Clinipro Antiaging SD, IMAGE DB system, Skin topography analysis, SELS parameters.