WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

  • WJPPS: NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2024 Issue has been successfully launched on NOVEMBER 2024.

Abstract

FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLETS OF METFORMIN HYDROCHLORIDE

Mohd. Junaid*, Zubair Alam and Deepak Kumar Kushawah

ABSTRACT

Sustained-release polymeric beads containing Ciprofloxacin Hydrochloride fabricated with sodium alginate and chitosan were prepared by the ionotropic gelation method. Model drug, ciprofloxacin hydrochloride was entrapped in sodium alginate and Gelucire in different ratios. Here, calcium chloride was used as a cross-linking agent. Microbeads of Ciprofloxacin hydrochloride were prepared with different concentrations of polymers and electrolytes. The microbeads were characterized in terms of drug-excipient compatibility study, particle size analysis, shape analysis, drug content, encapsulation efficiency and in vitro drug release study. Results signified the fact that microbeads formed had sufficient good surface and size to be utilized as a dosage form responsible for sustained release of drug from matrix through erosion.

Keywords: Sustained release, Microbeads, Sodium alginate, chitosan, Gelucire, Ionotropic Gelation, Ciprofloxacin HCl.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More