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ASSESSMENT OF ANTI-ULCER POTENTIAL OF UNRIPE FRUIT EXTRACT OF MUSA BALBISIANA IN STRESS INDUCED ULCER MODEL
Rafa Zubair N. V.*, Dr. A. Suresh, Dr. G. Babu , Asma M. A, Anupam Prahlad and Hanisha K. P.
ABSTRACT
The present study was carried out to evaluate the effect of aqueous unripe fruit extract of Musa balbisiana in the treatment of gastric ulcers. When severe stress is induced, the gastric mucosa of the experimental animals damaged due to the action of free radicals. Unripe fruit extract of Musa balbisiana have antioxidant potential due the presence of flavonoids (leucocyanidin), vitamins, phenolic compounds, triterpinoids etc. The dried powder of unripe fruits of Musa balbisiana was extracted with water by maceration for seven days and phytochemical analysis showed the Presence of alkaloids, flavanoids, tannins, phenolic compounds, terpenoids, saponins, carbohydrates, proteins, aminoacids, vitamin C, starch, pectin and tryptophan. Anti-ulcer potential of extract was evaluated by stress induced cold water immersion model. Wistar albino rats were divided Keywords: In-vivo anti-ulcer activity, Musa balbisiana, Stress induced ulcer, Cold water immersion. [Download Article] [Download Certifiate] |