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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

A REVIEW ON ENDOTHELIAL RECEPTOR ANTAGONIST

Gaju Sowmya Sri* and Dr. Challa Pradeep Kumar

ABSTRACT

The endothelin is a potent vasoconstrictor of smooth muscle cells and these endothelins are implicated in the vascular diseases of several organs including kidneys, heart, brain and lungs. These endothelin receptor antagonists are include selective and nonselective ETA and ETB receptors which are used in the treatment of several diseases. This endothelin receptor antagonist conducts clinical trials in congestive heart failure. Results in endothelin receptor antagonists reduced in the levels of hemodynamic. The objective of this review is to evaluate the available describing the pharmacology, efficasy, safty and tolerability in patients regarding the different types of endothelin receptor antagonist on randomized trials including a class of drugs that target a different cellular pathways believed to etiologically important in the congestive heart failure.

Keywords: Endothelin, Pharmacokinetics, Receptor antagonist.

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