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WOUND HEALING ACTIVITY OF POLYGONUM BARBATUM LINN. (WHOLE PLANT)*Hitesh Kumar Kinger1, Mahesh Kumar Gupta2
1Department of Pharmaceutical Sciences, CMJ University, Shillong Meghalaya, INDIA. 2Kota College of Pharmacy, Ranpur, Kota (Rajasthan) INDIA.
ABSTRACT Polygonum barbatum Linn (Polygonaceae), commonly known as Bearded Knotweed, Water milkwort, is a commonly available plant in India. This plant has been used in the treatment of cuts by the people living in Andhra Pradesh. The ethanol and aqueous extracts of Whole plant of Polygonum barbatum were prepared and its wound healing and antioxidant activity were evaluated. The wound healing activity was studied using two wound models, excision wound model and incision wound model. The extracts responded significantly in both the wound models tested. Comparatively, the aqueous extract was found to be more effective. These findings could justify the inclusion of this plant in the management of cuts by the local people. Keywords: Excision; Incision; Wound healing; Povidine-iodine. [Download Article] [Download Certifiate] |