Abstract

DEVELOPMENT OF UV SPECTROPHOTOMETRIC METHODS FOR THE ESTIMATION OF SAROGLITAZAR

Rucha V. Pancham*, Dr. Milind J. Umekar and R.T. Lohiya

ABSTRACT

A new, simple, precise, accurate, reproducible and economical and sensitive UV ‐ Spectrophotometric method has been developed for the estimation of Saroglitazar in bulk and pharmaceutical dosage form. The determination was made at 295 nm for Saroglitazar over the concentration range of 4-24 μg/ml with mean recovery of 99.95%.Methanol was used as solvent.0.1NHCL was also used as a cheaper solvent over methanol and method was developed over the concentration range as same as that of methanol. The drug follows Beer’s Law in the concentration range of 4-24ug/ml. The validation of method was carried out as per ICH Guidelines.

Keywords: Saroglitazar, UV Spectrophotometric method, validation, Lipaglyn Marketed formulation.