Abstract

LDH: A PROGNOSTIC MARKER IN PRE-ECLAMPSIA- ECLAMPSIA: AN OBSERVATIONAL STUDY IN A NORTH EASTERN STATE OF INDIA MEGHALAYA

Priti Mishra*, Ragini Thapa and Arvind Kumar Dinkar

ABSTRACT

Background: Pre-eclampsia is a major cause of maternal and perinatal mortality and morbidity worldwide causing 24% of all maternal deaths in India. LDH is a intracellular enzyme which is a marker of severity of pre eclampsia. The present study is an endeavour to assess prognostic importance of LDH in pre eclampsia. Methods: The study comprised of 50 women with singleton pregnancies with between 28 to 40 weeks of gestation complicated by preeclampsia admitted to Military Hospital, Shillong from March 2017 to February 2018. They were compared to 50 normotesive women admitted between the same time frame. Results: Women with pre eclampsia with severe features were typically young and primigravida. High serum LDH is associated with various maternal and perinatal complications like. Conclusions: Increased LDH is a prognostic marker of pre eclampsia with severe features .It can be used as a marker for early detection of pre eclampsia with severe features.Early detection can facilitate timely detection of patients with high risk patients.

Keywords: Pre eclampsia, Gestational hypertension, LDH, LFT, Prognosis.