Abstract

A REVIEW ON TRANSDERMAL PATCHES

Shyam Skumar*, Mohammed Navas, Silji T. S., Anju S., Bhagyasree G., and Fathimathul Mubashira M.

ABSTRACT

Depending on the therapeutic target, transdermal drug delivery systems (TDDS) are designed to provide a continuous supply of drug through the skin to allow for local or systemic drug effects. The purpose of this descriptive review is to introduce practical theories behind TDDS. Appropriate use and disposal of TDDS are dictated by the active ingredient, patchtype and several patient-specific characteristics such as age, gender, skin integrity and organ function. Transdermal delivery has many advantages over conventional modes of drug administrations, it thus avoids hepatic first pass metabolism and improves patient compliance. Transdermal systems are convenient and therapeutically beneficial for select patient types. Appropriate application, disposal and monitoring techniques can optimize care for patients, care givers and the general public.

Keywords: TDDS, Skin absorption, Cutaneous drug transport, Transdermal patches.