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Citation | 5450 | 3969 |
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NEW POTENT HETEROCYCLIC BISPHOSPHONATE API (ZOLEDRONIC ACID): A REVIEW
Himmat Singh*,Swatantra Ku. Mishra, Sandeep Singh Parihar, Rahul Sharma and Shikha Jain
ABSTRACT Zoledronic acid is a new, highly potent bisphosphonate drug. Bisphosphonates is a class of chemical compounds finding extensive medical applications against bone disorders including osteoporosis, Pagets’ disease, etc. Non-N-containingmembers include etidronate, clodronate Andtiludronate, while N-containing bisphosphonates include active pharmaceutical compounds Such as pamidronate, neridronate, olpadronate, alendronate, ibandronate, risedronate and zoledronate. The present study covers 20 years of analytical researchon this groupofcompounds, focusing on bioanalytical and pharmaceutical QC applications. Keywords: Bisphosphonates (Zoledronic acid), ion-pair RP-LC, Radio-immunoassay and Pharmacokinetics. [Download Article] [Download Certifiate] |