Abstract

A NOVEL APPROACH TOWARDS THE TREATMENT OF BARIATRICS

Dr. Syed Mohammed Kazim, Fareeaa Ashar*, Mohsina Abid, Nahid Begum, Salma Shaheen and Syeda Sumayya

ABSTRACT

Over weight and obesity are rising medical conditions. There are many detrimental health effects of obesity such as CV diseases, diabetes, high cholesterol etc. The traditional methods to overcome obesity by using antihyperlipedemic drugs which have side effects such as stomach pain, diarrhoea, leakage of oily stools etc. To overcome these side effects, there is a need to develop a nobel method for treatment of obesity. One novel approach to treat obesity is “inhibition of fat absorption in GIT”. This can be achieved by formulating a tablet using absorbent such as kaolin and talc. Five batches of floating tablets with variable concentration of absorbents are formulated and named as F1- F5 formulations. F5 formulation is optimized due its high swelling index of 144.85 and high floating duration of 18 hours. The tablet will float in GIT remains non disintegrated and absorbs all the fats present in the GIT, thus inhibiting fat absorption by the body. The tablet with absorbed fat will be eliminated from the body as such. This novel approach towards bariatrics will not have side effects and hence preferable over traditional drugs for the treatment of obesity.

Keywords: Anti hyperlipidemic, fat absorbing tablets, bariatrics, obesity.