Abstract

DESIGN, EVALUATION AND COMPRATIVE STUDY OF IN VITRO ANTHELMINTIC ACTIVITY ON SAP OF AZADIRACHTA INDICA AGAINST HELMINTHIASIS MODEL

Tribhuvan Singh*, Jogu Chandrudu and Pooja Parmar

ABSTRACT

The current study was designed and evaluated to in vitro anthelmintic activity in helminthiasis model on Sap of Azadirachta indica. The duct roundworm has been reported to cause severe health issues in immeasurable folks round the world. Records prove that a lot of the liquid extracts obtained from varied elements of various seasonal plants exhibited important Anthelmintic activity against helminthiasis model. This gave us a lead to found new compound resulting in the Anthelmintic activity on Sap of Azadirachta indica. The vermicidal activity was studied in four completely different volumes (5, 10, 20, 40 ml) and dilutions (5/15, 10/10, 15/5, 20/0) millilitre were prepared. The dilutions were evaluated for the time of paralysis and time of death of the worm. Sap of Azadirachta indica exhibited excellent Anthelmintic activity in helminthiasis model. At highest concentration of 40 millilitres and dilution’s 20/0 millilitre exhibits excellent Anthelmintic activity was reported as compared to standard drug, Albendazole. Sap of Azadirachta indica in vitro studies indicated that Sap of Azadirachta indica possess excellent Anthelmintic activity in helminthiasis model.

Keywords: Sap of Azadirachta indica; Pheretima posthuma; Anthelmintic Activity, Helminthiasis Model.