Abstract

PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL SCREENING OF ABUTILON INDICUM SWEET LEAVES EXTRACT

Vidya Nalawade*, Dr. Pramodkumar Shirote, Priyanka Majalekar, Priyanka Shelake, Vikram Nalawade

ABSTRACT

Many of the phytoconstituents were traditionally reported for dreadful aliments, are nowadays found to be exhibit interesting bioactivity and have cardinal output. One noticeable striking example is use of plant Abutilon indicum in various ailments. The plant parts reported to have medicinal value and used by local community in various diseased conditions. The thirst of present work is to isolate active constituent from leaves of the plant Abutilon indicum sweet and avail about its antipyretic activity. Extraction of leaves of plant was carried out by soxhlet apparatus. Phytochemical analysis was conducted to identify nature of chemical constituent present in the plant. Isolation and identification was conducted by chromatographic techniques. Isolated fractions were characterized using data obtained from spectral analysis. Antipyretic effect of plant extract was studied on yeast induced pyrexia. The study demonstrated the isolated fractions were betasitosterol and quercetin which hypothetically may responsible for antipyretic activity. Extract showed significant antipyretic activity as compared to standard. Novel biologically active natural products will continue to serve as lead compounds for drug development and is biochemical probes for the discovery of pharmacological and biochemical process.

Keywords: Abutilon indicum, chloroform extract, antipyretic.