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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

AEGLE MARMELOS: DOWN-REGULATOR OF ANGIOGENESIS IN CHICK CHORIOALLANTOIC MEMBRANE (CAM) IN OVO

*U. H. Shah

ABSTRACT

The chick chorioallantoic membrane (CAM) is ideal model for study of vasculogenesis and angiogenesis. The sprouting type of angiogenesis is present in chick CAM up to 5- 6 embryonic days of incubation. The effect of aqueous leaf extract of A. marmelos was studied on angiogenesis by using chick CAM assay. The aqueous leaf extract significantly decreases the area of CAM, number of blood vessels and capillary plexus formation. The phytoconstituents in A. marmelos acts synergistically as angiostatic and may be used in therapeutic angiogenesis to treat disease like cancer in which excessive angiogenesis is observed.

Keywords: Angiogenesis; Aegle marmelos; Chick CAM.

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