Abstract

A RARE CASE OF MULTIPLE ORGAN DYSFUNCTION SYNDROME WITH CEREBRAL MALARIA, BRONCHOPNEUMONIA AND ENCEPHALITIS

G. D. S. Chaitanya*, Namagiri Manisha, Pakki Kausik and Sakhamuri Navyasri

ABSTRACT

Multiple organ dysfunction syndrome (MODS) is a continuum, with incremental degrees of physiologic derangements in individual organs; it is a process rather than a single event. The condition usually results from infection, injury (accident, surgery), hypoperfusion and hypermetabolism. The primary cause triggers an uncontrolled inflammatory response. Sepsis is the most common cause of Multiple Organ Dysfunction Syndrome and may result in septic shock. Symptoms of sepsis are usually nonspecific and include fever, chills, and constitutional symptoms of fatigue, malaise, anxiety, or confusion. In this case the patient of age 60 years female was admitted in the hospital with a complaint of fever and altered sensorium. The patient was diagnosed with MULTIPLE ORGAN DYSFUNCTION SYNDROME, CEREBRAL MALARIA, BRONCHOPNEUMONIA AND ENCEPHALITIS. Patient was treated with nor adrenalin, anti malarials, corticosteroids, nebulisations, antibiotics, vitamin supplementations and supportive therapy. After the course of treatment, patient was considerably stable. As clinical pharmacists we counseled guardians of the patient regarding factors aggravating the disease, importance of medication adherence and dietary requirements. Regular visits to the hospital were advised.

Keywords: Multiple organ dysfunction syndrome (MODS), cerebral malaria, bronchopneumonia, encephalitis.