Abstract

INVITRO ANTI INFLAMMATORY ACTIVITY OF LEAVES EXTRACT OF PAVONIA ZEYLANICA CAV

Pitchiah Kumar M.*, Sivasankar, Senthilvel G. and Lakshmipathy Prabhu. R.

ABSTRACT

Pavonia zeylanica Cav. (Familiy -Malvaceae) is a valuable medicinal plant which has been used in siddha system of medicine. The leaves extract of Pavonia zeylanica Cav was assessed for its anti inflammatory activity by invito methods. Invitro activity were evaluated using bovine albumin denaturation assay and membrane stabilization activity using HRBC method. Diclofenac used as standard drug. The ethanolic extract of Pavonia zeylanica Cav leaves at various concentrations (100,200,400 and 800μg) showed significant inhibition in bovine albumin denaturation assay and showed the significant membrane stabilizing action on human red blood cell membrane. Based on results the present study shows that ethanolic extract of Pavonia zeylanica Cav can be a better alternative source of anti-inflammatory agents.

Keywords: Anti-inflammatory, Pavonia zeylanica Cav, Diclofenac sodium, Bovine albumin HRBC Membrane stabilization.