ANTI-HYPERLIPIDAEMIC EFFECT OF BOMBAX CEIBA BARK AND SEEDS POWDER ON ALBINO WISTAR RATS
Akriti Singh*, Dr. Ekta Singh Chauhan and Dr. Om Prakash Singh
ABSTRACT
Objective: The present study was aimed to investigate the antihyperlipidaemic
activity of Bombax ceiba bark and seeds powder on
high fat high cholesterol (HFHC) fed rats group. Methods: Male
Albino Wistar rats were fed by HFHC diet to create hyperlipidaemic
condition in them. The rats were fed by Bombax ceiba bark and seeds
powder at 200mg/kg body weight of rats. The effect of both the
powders on serum and tissue lipid profile was determined, including
albumin, protein, phospholipid, free fatty acid, triglycerides and total
cholesterol (HDL-C and LDL-C) levels was studied. In addition, body
weight changes, organs weight, relative liver size and food
consumption were also evaluated in HFHC diet fed rats. Results: Supplementation of bark
and seeds powder of Bombax ceiba showed the significant reduction in serum and tissue
phospholipid, free fatty acid, triglycerides, total cholesterol, LDL-C levels and increases the
protein, albumin, HDL—C level as well in experimental groups as compare to HFHC fed
group. There was a significant elevation in the value of phospholipids, free fatty acid,
triglycerides, LDL-C, total cholesterol and decrease in albumin, protein, HDL-C in HFHC
fed rats groups. Hence, the results justify that Bombax ceiba possess anti-hyperlipidaemic
activity. Conclusion: Bombax ceiba bark and seeds powder is an effective alternative for the
treatment of hyperlipidaemia as it reduces the lipid level in serum as well as in tissues.
Keywords: Bombax ceiba, Hyperlipidaemia, Phospholipid, Triglycerides, Cholesterol.
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