Abstract

A CLINICAL EVALUATIN OF KHADIRADI VATI IN TAMRAPARNA (NICOTIANA TABACUM) ATISEVANJANYA MUKHAGATA VISHA LAKSHAN

Dr. Ruta Kadam and Dr. Debasish Satpathy*

ABSTRACT

Excessive tobacco consumption by way of smoking or chewing its various products is the etiological factor of more than 25 diseases. Tamraparna (Nicotiana Tobacum) stated as sthavara visha and a cardio toxin on excessive and consumption results in symptoms of oral toxicity. Considering the ever increasing incidence of the disease, a study was planned with an aim to clinically assess the efficiency of Khadiradi Vati in Tamraparna (Nicotiana Tabacum) Atisevanjanya Mukhagata Vishalakshan. An open clinical trial was conducted and a total of 52 patients were screened 30 patients showed symptoms in accordance with the criteria of assessment and fulfilling the inclusion criteria. Who completed the trials whereas 10 patients were dropped out for various reasons. Some of the commons symptoms formed the subjective criteria of assessment viz. Oshthachimchimayan, Jihvajadyata, Mukhadaha, Dantamoola shotha etc and were graded on the basis of severity. Hanusthambha was the objective criteria measured using a Vernier caliper, Khadiradi vati was administered, 250mg thrice daily to be sucked, for 15 days and regular follow-ups were taken. Informed consent was taken prior to enrolment in the study. The results were analyzed using the Wilcoxon Signed Rank test and significant efficacy was noted in Dantaharsha, Mukhadaha, Mukhadautgandhya, Vaivarnyadanta, Dantamla shotha, Mukhapaka and Hanusthambha. A conclusion was drawn that K.V. is effective Tamraparna (Nicotiana Tabacum) Ati sevanjanya Mukhagata Visha lakshan.

Keywords: Tobacco, Khadiradivati Mukhagata, Vishalakshan, Oral toxicity, Tamraparna.