Abstract

ALLIUM SATIVUM AS ANTI-ALLERGENS

Ruchi Singh*, Dr. Afroze Alam, Dr. Rashmi Kumari, Dr. V. P. Dubey and
B. D. Tripathi

ABSTRACT

Allergy is a condition in which the immune system reacts abnormally to a foreign substance. It mainly occurs due to hypersensitivity of the immune system and releases the damaging histamines. Allergies may affect the whole body. It especially affects the skin, nasal passage, eyes and lungs. Eating two raw cloves of Allium sativum is very much effective and even its juice keep the doctor away. Eating raw Allium sativum everyday fights against all types of allergies. Allium sativum boost the immune system. In this research, extracts have been prepared of Allium sativum. As extracts of several spices have been reported to play a vital role in enhancing immunological function. The evaluation of oral administration of fresh aqueous Allium sativum extracts at different concentrations in rats were estimated and by which total and differential White Blood Cell counts were recorded and our findings revealed that total WBC counts were significantly increased (P≤0.05) in a dose dependant manner revealed that total WBC counts were significantly increased (P≤0.05). In garlic extract (300mg/kg/d: 420±20cell/ul and 3.01 ± 0.10×103 cell /l; 600 mg/ kg/d: 498 ± 35cells/ ul and 2.98± 0.15×103cell/ l; 850mg/ kg/d: 680±10cell/μl and 3.66±0.02×103cell/l) all treated rats were compared with the zero control i.e. 198±10cells/μl and 1.66±0.02×103cells/l, respectively. At 850 mg/kg/d had significantly increased the total white blood cell count when it was compared with the other concentrations (P≤0.05).

Keywords: Allium sativum, allergy, immune system.