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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

A REVIEW ON RP-HPLC OF ANTI TUBERCULAR DRUGS

*Saher Shah Khan and Shaik Mahammad Noorulla

ABSTRACT

A review on rapid, simple, and sensitive, stability indicating high performance liquid chromatographic method for the simultaneous determination of rifampicin, isoniazid and pyrazinamide, ethambutol, levofloxacin and other anti-tubercular drugs in different pharmaceutical samples by using different chromatographic column {Phenomenex c-8, Luna (250x4.6mm,5 μm), Hypersil c8 (4.6x250nm,5 μm), Inertsil (250x4.6x5μ) column,Waters XTerra RP18, 5 μm, 250 mm X 4.6 mm,C18column, (KromasilODS, 5m, 250 × 4.6mm), Zorbax Rx-C18 5μ column (150 x4.6mm)}, using different mobile phase{ 0.3M sodium citrate ph:5 with glacial acetic acid, Ammonium acetate: Acetonitrile (30:70v/v), Dichloromethane: Methanol: Formic acid (70:30:0.1 v/v/v)}. The method is detected by UV detector in limits ranging from 205-308 nm.

Keywords: RP-HPLC, Review, Anti tubercular, Method Development, Validation, Stability Indicating.

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