Abstract

EVALUATION OF ANTIULCER ACTIVITY OF ACONITUM HETEROPHYLLUM ON EXPERIMENTAL ANIMAL

Vishal R. Rasve*, Vivek V. Paithankar, Mrunal K Shirsat, Avinash V. Dhobale

ABSTRACT

In present era peptic ulcer is a worldwide problem and its prevalence is quite high in India. Some present data shows that in different part of India its occurrence is 4 to 10 % per thousand populations. The exact etiology of peptic ulcer is not known, the disease results in chronic suffering, loss of working hours and occasional fatality. Smoking habit, alcoholism, stress & spicy food make the severity of the disease which leads serious complication of ulcer. Aconitum heterophyllum is one of the most commonly use in different medical conditions has been documented. Traditionally, Aconitum heterophyllum roots or tubers are beneficial in the treatment of diseases related to lungs & airways, blood, skin, stomach, intestines, and liver. As no reports are available on the possible antiulcer effects of Aconitum heterophyllum. The present work was carried out to antiulcer activity of Aconitum heterophyllum by cold stress induced gastric ulcers in wister albino Test drug Aconitum heterophyllum ( low dose) and Aconitum heterophyllum (high dose) have shown result in comparison to standard drug omeparazole and control drug. Thus study has provided documentary evidence for antiulcer property of Aconitum heterophyllum for its activity.

Keywords: Aconitum heterophyllum, peptic ulcer, antiulcer property.