Abstract

REVIEW OF DETERMINANCE AND OVERVIEW TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE(COPD)

Chandragiri Naveen Kumar Reddy*, Harshith A. S., Jacob N. Thomas, Vanendra Yadav S. and A. Vikneswari

ABSTRACT

Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by chronic airway inflammation, a decline in lung function over time, and progressive impairment in quality of life.[1] In chronic obstructive pulmonary disease (COPD), airflow is obstructed during expiration. This increases the work of breathing and causes dyspnea. In contrast to asthma, the airflow obstruction is not reversible and usually progresses over time. There are several mechanisms of airflow obstruction in COPD. Chronic bronchitis results in hypersecretion of mucus which fills and obstructs the airway lumen. Inflammation and fibrosis of the airway mucosa and surrounding tissue (obliterate bronchiolitis) cause airway wall thickening. Emphysema causes loss of the alveolar attachments which normally hold the airway open.[2]

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