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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

EFFECT OF HPMC VISCOSITY (TYPES) ON MEBEVERINE HCL 200MG TABLETS EXTENDED RELEASE

Dr. Mohammed Al-Halili*, Abdul Kareem Mohammed and Safaa Ahmed

ABSTRACT

In vitro release of Mebeverine HCl 200mg embedded in an extended release (ER) matrix, composed of various viscosity types of Hydroxy-propyl methylcellulose (HPMC), with Microcrystalline cellulose (MCC 102), Lactose anhydrous, Magnesium stearate, and Aerosil, was investigated, to study the effect of change of HPMC viscosity (5,15,50,4000, 10000, and 100000 mpas) in Mebeverine HCl release from tablet prepared by dry granulation method, release was studied for 13hrs, and release difference was clearly observed by changing HPMC viscosity.

Keywords: Mebeverine HCl, Extended Rrelease, Hydrophilic Matrices, Hypermollose, Hydroxypropyl methylcellulose, HPMC, Dry granulation.

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