Abstract

FORMULATION AND EVALUATION OF POLYHERBAL ANTI ACNE CREAM

Mansi Doshi*, Neelmani Chauhan, Janmajoy Banerjee and H. Padmalatha

ABSTRACT

Acne by definition is multifactorial chronic inflammatory disease of pilosebaceous units. Propionibacterium acnes and staphylococcus epidermidis are considered as the major skin bacteria that cause the formation of acne. Although acne does not pose serious threat to general health, it is one of the most socially distressing conditions especially for adolescents. In the present study, poly herbal anti acne cream was prepared using extracts of the plants Azadirachta indica, Symplocos racemosa, aloe vera along with base materials. The plants have been reported in the literature having good anti- microbial, anti- oxidant and anti-inflammatory activity. Five formulations of the cream were prepared by varying the proportions of polymers and evaluated for their physicochemical property like pH, spreadability, viscosity, homogeneity, appearance, after feel and spreadability like tests. Among the 5 formulations the formulations 3 and 4 shows better results in evaluation. The main objective is to prepare a cream with natural herbal extracts and minimize the side effects of the chemical cosmetics.

Keywords: Anti acne, Polyherbal cream, Aloe vera, Azadirachta indica, Symplocos racemosa.