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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

IN VITRO ANTIULCER ACTIVITY OF CHLOROFORM EXTRACT OF POLYHERBAL FORMULATION AGAINST HELICOBACTER PYLORI

Sumia Fatima*, Dr. C. Ramesh and Abdul Saheel Qureshi

ABSTRACT

The present study was performed to assess the in vitro effect of chloroform extract of Polyherbal formulation AET against Helicobacter pylori strain using Agar disk diffusion and broth microdilution methods to determine the minimum inhibitory concentration (MIC) values. In agar disk diffusion assay, the chloroform extract of Polyherbal formulation AET showed maximum zone inhibition of 12.975±1.13 mm at 500mcg/ml concentration whereas, in broth microdilution assay, the minimum inhibitory concentration (MIC) of the extract by visual examination was found to be at 125 mcg/ml. The results were compared with clarithromycin 15 mcg as standard. The study reveals that the chloroform extract of PHF AET may contain compounds possessing antimicrobial activity and thus can be used as an alternative medicine for gastrointestinal diseases.

Keywords: Agar Disk Diffusion Assay, Broth Microdilution Assay, MIC, Polyherbal formulation AET.

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