Abstract

IN SILICO ANTICANCER ACTIVITY OF TETRADECANE 2-METHYL IN ACANTHOPHORA SPECIFERA (RED SEAWEED) COLLECTED FROM GULF OF MANNAR, TAMILNADU, INDIA

*R. Rajeshkumar and K. Jeyaprakash

ABSTRACT

Acanthophora Specifera is a species of marine red seaweed and in the family Rhodomelaceae. They were freshly collected from Mandapam Coastal Area, Rameswaram Tamilnadu, India and rinsed in seawater and packed in aseptic bags for further proceedings to laboratory. Seaweeds are potential renewable resources in the marine environment. It has been used as antioxidant and antimutagen. Methanol extract was prepared for further analysis. Molecular docking and modeling studies improve the reliability, accuracy of biological test and show possible interactions between molecules and their target receptors. So in present study Tetradecane 2-methyl identified by GC-MS study were subjected to molecular docking for better recognition of their interaction in Nuclear factor kappa B (NFkB).

Keywords: Red Seaweed, Insilico study, Acanthophora specifera, Molecular Docking, Nuclear factor kappa B(NfKB).