Abstract

RATIONALE OF DERIPHYLLINE IN COPD PATIENTS AMONG URBAN POPULATION

Swathi S.*, Subhashini Vedagiri Radhakrishnan* and Santhosh Kumar V.

ABSTRACT

COPD is one of most common chronic disease affecting 0.5-1% of world’s population that predominately in women. Emotional stress, air pollution, passive smoking and food habits play an important role in COPD. This present study is to ascertain rationality with of fixed dose combination-Deriphylline (theophylline and etophylline) SR in COPD patients after classifying according to GOLD guidelines in urban population. Patients were included in this study after receiving the patient consent form according to the ethical committee. Measurements such as Borg dyspnoea scale, St. George’s respiratory questionnaire, Medical research council (MRC) breathlessness scale. Clinical evidence supports the effectiveness of multiple drug therapies, however in the absence of long term data. The purpose of this research is to provide an overview of different clinical approaches and highlight some of the important issues surrounding the choice of drugs to be used in COPD. The purpose of this research is to provide comprehensive disease management strategy, which included a patient education session, a self-treatment plan for exacerbations and a monthly follow-up, is associated with a lower hospitalization rate. This study is also designed to alleviate symptoms; to prevent exacerbations; to preserve optimal lung function; to improve activities of daily living, quality of life and survival; with minimal adverse effects from treatment.

Keywords: COPD, Deriphylline, GOLD Guidelines.