Abstract

A REVIEW ON SOLANUM NIGRUM

Yerukali Sudha Rani*, V. Jayasankar Reddy, Shaik Jilani Basha, Mallapu Koshma, G. Hanumanthu and P. Swaroopa

ABSTRACT

Medicinal plants are extensively used to cure various infectious diseases in human beings, hence Solanum nigrum, was investigated for its activity against the isolated pathogens from sputum samples. The study was designed to screen and characterize the bacteria isolated from the respiratory tract infected patients. Aqueous, ethanol and diethyl ether extract of solanum nigrum was prepared; four different concentrations of each extract were taken to determine the anti-bacterial activity against the isolated bacteria. The ethanolic extract of Solanum nigrum showed highest antimicrobial activity in comparison to aqueous and diethyl ether extracts. Phytochemical analysis of the plant showed the presence alkaloids, terpenoids, flavonoids, saponins, steroids and phenols. Thus Solanum nigrum has anti-microbial activity and can be used clinically to find novel antibacterial compounds for respiratory tract pathogens.

Keywords: Solanum nigrum, anti-cancer activity, carcinogenic.