Abstract

HISTOPATHOLOGY OF ORAL SQUAMOUS CELL CARCINOMA –A REVIEW

Sravanthi Vuppu, Varun Kumar, Maumita Bhattacharya, Himanshu Thukral*, Shruti Mehta, Pallavi Prakash and Anubhav Agarwal

ABSTRACT

Squamous cell carcinoma is one of the most common malignant tumor of oral cavity. Smoked and smokeless form of tobacco, alcohol, diet and immunosuprression are the main aetiological factors in oral cancers. Grading and cytomorphology of the neoplasm serve as a precise measure for predicting the outcome of the neoplasm and for treatment planning. Border was the first to initiate the quantitative grading of cancer. Histopathological grading is an important factor in determining the prognosis of oral carcinoma. Oral squamous cell carcinoma has a high malignant potential with great propensity for metastasis to the regional lymph nodes through vascular invasion and thereby leading to loco regional failure.

Keywords: Grading, Metastasis, Oral squamous cell carcinoma.