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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR VETIVER OIL IN MICROSPHERE FORMULATION BY UV SPECTROSCOPIC METHOD

Syed Ansar Ali*, T. Sreenivasa Rao, Kripa Srestha and Kalyan Kumar Sen

ABSTRACT

In the present work, simple and sensitive UV spectroscopic method has been developed for the quantitative estimation of Vetiver Oil in microsphere formulations. Methanol was used as solvent. In the range of 10-35 μg/ml, the linearity of Vetiver Oil shows a correlation co-efficient of 0.998. The UV detection wavelength was 235nm. The percentage RSD for precision and accuracy of the method was found to be less than 2%, (LOQ) of 4.247 μg /ml and (LOD) of 0.556 μg/ ml. The method was validated as per the ICH guidelines. The method was successfully applied for routine analysis of vetiver oil microsphere formulation dosage form.

Keywords: vetiver oil, UV Spectroscopic Method, recovery, precise.

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