Abstract

ANTIMICROBIAL ACTIVITY OF 1-(4-(1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PHENYL)-5-METHYL-3-ARYL-1,3,5-TRIAZINANE-2-THIONES AND 3-(4-(1H-IMIDAZO[4,5-B]PYRIDINE-2-YL)PHENYL)-5-ARYL-1,3,5-OXADIAZINANE-4-THIONES

G. Dayakar, Dr. A. Jeyanthi* and R. Ajay Kumar

ABSTRACT

The 1-(4-(1H-imidazo[4,5-b]pyridin-2-yl)phenyl molecule (I) reacts with MeNH2 , CH2O to give triazinane thiones (II) and with CH2O to give Oxadiazinane thione (III) derivatives of it. The antimicrobial activity of these new compounds with various substituents have been reported in the present study.

Keywords: Triazinane thiones, Oxadiazinane thione, Impregnated discs, Degree of Inhibition.