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Abstract

STUDIES ON THE HEPATOPATHOLOGICAL EFFECT OF BENZENE HEXACHLORIDE ON A TELEOST FISH, CYPRINUS CARPIO COMMUNIS

Dr. Rakesh Singh, Dr. Ajit Hundet* and Barun K. Prabhat

ABSTRACT

We investigated the histopathological changes in the structure of liver cells in response to three and five part per million concentration of benzene hexachloride (BHC) under light microscopy with a view to analyze the damages caused because of extensive use of the pesticide. We found that in response to 3-and 5-ppm BHC intoxication, liver showed gangrene formation, vacuolization, sponginess, complete separation of blood vessels from hepatic cells, atrophy of hepatic nucleus in addition to shrinking of pancreatic tissue. Our studies indicate that the organochlorine pesticide, BHC, is very detrimental for the aquatic system as it produced pronounced alterations in the organ.

Keywords: BHC, shrinking, sponginess, liver, gangrene, vacuolization.


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