BIOLOGICAL SCREENING PROCEDURES FOR ANTI-DIABETIC DRUGS-A REVIEW
M. Ramanathan* and N. Venkatesan
ABSTRACT
Appropriate experimental models are essential tools for understanding the pathogenesis, complications, and genetic or environmental influences that increase the risks of type 2 diabetes and testing of various therapeutic agents. The animal models of type 2 diabetes can be obtained either spontaneously or induced by chemicals or dietary or surgical manipulations and/or by combination thereof. This review gives an overview on the animal models of type 2 diabetes with reference to their source, characteristic features, underlying principal and procedure to the investigators in diabetes research.
Keywords: Diabetes is a complex and heterogeneous disorder presently.
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