Abstract

DETERMINATION OF IN VITRO ANTIOXIDANT ACTIVITY OF SESAMUM PROSTRATUM RITZ (PEDALIACEAE) WHOLE PLANT

Palanisamy Arunkumar, Rajan Michael Evanjaline and Muthaiya Anandi Ravichandrun*

ABSTRACT

Antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of Sesamum prostratum whole plant have tested using various antioxidant model systems viz., DPPH, hydroxyl, superoxide and ABTs. Methanol extract of S.prostratum is found to possess highest DPPH, hydroxyl and ABTs radical cation scavenging activities. The superoxide radical scavenging activity of S.prostratum, ethanol extracts records the highest. Like the antioxidant activity, reducing power of the extract increases with increase in concentration. This study indicates significant free radical scavenging potential of S.prostratum whole plant which can be exploited for the treatment of various free radical mediated ailments.

Keywords: Sesamum, Antioxidant, DPPH, Methanol, Flavonoid.