Abstract

ANTI-INFLAMMATORY ACTIVITY OF BENZENE EXTRACT OF ABIES WEBBIANA LINDL. (FAM-PINACEAE) LEAVES

Dr. Nityananda Sahoo* and Dr. Tarun Jha

ABSTRACT

The chemical diversity within the natural products is an immensely rich source of new pharmaceuticals, cosmetics and other economically important chemicals. Presently, numerous pure compounds are being isolated from plant sources having very promising therapeutic profiles. Now, the synthetic drugs are gradually sidelined by phytomedicines due to their adverse effects and the inability to provide complete cure in certain diseases and disorders in a cost effective manner. The present study was done to evaluate the therapeutic potential of the plant leaves of Abies webbiana. The anti-inflammatory activity of benzene extract of Abies webbiena leaves was investigated by carrageenan-induced rat hind paw edema method using mercury displacement technique with the help of travelling microscope. The benzene extract showed significant activity in a dose dependent manner as compared with standard drug diclofenac sodium. The extract containing tannins which have significant role of free radical scavenging may have the ability to produce anti-inflammatory activity.

Keywords: Abies webbiana, Anti-inflammatory activity, Carrageenan, Diclofenac sodium.