Abstract

EVALUATION OF FOOT CREAMS FORMULATION ON HUMAN SKIN – A NOVEL APPROACH

Venkataramana Arbettu Padmanabha, Jayaganesh Sankar* and Jainendra Malakar

ABSTRACT

The skin on our feet is naturally dry, because in feet there is no oil gland like rest of the body. The foot skin can become dry for a number of reasons, but there are ways to prevent it, such as keeping our feet moisturized and avoiding rubbing or scratching the skin. In general cracked heels are noticed in the elderly aged female when compared to the young age girls. Similarly these problems are very much pronounced in elderly female than male. Foot cracks open the entry path of bacteria to the body, and it may lead to promote the foot ulceration, microbial attach and lead to amputation also. The present study aims to measure the hydration property and hydration lock property of foot cream measured with help of carneometer. In addition to that, the present study deals about the wound healing properties of new developed formula. This article covers the detailed quantification of anti-microbial and anti-fungal screening and it will helpful to generate the optimum formula for the end user with respect to moisture benefit and healing property of foot cream. In the case of tested leading bench mark initially increase up to 17 unit and reach the 12.6 unit after 12 hours. This result indicates the alarm of next application of cream. Study results revealed daily two times application of foot cream maintain the skin moisture and prevent from the skin damage issues. Based on primary study results indicates that the option 2 sample was better when compared to option 1 and tested bench mark sample. Antibacterial and antifungal activity of samples and bench mark found to be highly significant when compared to the standard. The study reveals that the wound healing activity of both sample and standard found to be highly significant (p < 0.001) when compared to control. However the in-house samples are having the slightly leading edge when compared to the bench mark samples.

Keywords: Foot cream, heal cream, carneometer, dry skin, anti-fungal, anti microbial, wound healing.