Abstract

STUDY OF BACTERIAL PATHOGENS IN URINARY TRACT INFECTION AND THEIR ANTIBIOTIC RESISTANCE PROFILE

Jyotsana Sawant* and Yeshwant Khillare

ABSTRACT

Analyzing antibiotic susceptibility pattern of uropathogens help to overcome the therapeutic difficulties created by the rising antimicrobial resistant bacteria and guides in choosing appropriate antibiotics. evaluating the pathogens causing UTI and study their antibiogram. Midstream urine samples were collected, cultured and appropriate biochemical tests were performed for identification of urinary pathogens from June 2016 to December 2016. The most common isolated Gram negative uropathogens were Escherichia coli (73.33%) followed by other bacterial species, named Pseudomonas spp. Enterobacter Acinetobcter and non- lactose fermenting gram negative bacteria. Among Gram positive organism S. aureus and Enterococci were found. High level of sensitivity was found to imipenem, amikacin, nitrofurantoin, ceftriaxone, piperacillin + tazobactum, cefuroxime in most of the isolates. Almost all organisms exhibited multiple antibiotic resistances. The high multiple antibiotics resistance identified makes it necessary for testing of antibiotic susceptibility to be conducted prior to antibiotic(s) prescription.

Keywords: Urinary Tract Infection, Uropathogens, Imipenem, Amikacin, Nitrofurantoin, Piperacillin +Tazobactum.