TOPOLOGICAL INDICES & INDICATOR PARAMETERS USED IN PIPERDINE-4-CARBOXAMIDE DERIVATIVE CCR5 ANTAGONIST (TAK-220) WITH ANTI-HIV-1 ACTIVITY
*Neelu Agrawal
ABSTRACT
QSAR studies on Anti HIV-1 activity of Piperidine-4-Crboxamide Derivatives have been discussed. The topological, indicator parameters and biological activities were used. The predictive power of the model was examined using a CCR5alogIC50.
Keywords: QSAR, Anti HIV-1, Topological indices, indicator parameters and CCR5alogIC50.
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