Abstract

METHODS, TYPES AND APPLICATIONS OF PHARMACEUTICAL POLYMERS

Priyanka Shinde*, Manodaya Patil and Akshay Patil

ABSTRACT

The current review article focuses on polymers in pharmaceutical industry which is use for drug delivery and manufacturing of dosage forms. There are various types of polymers which varies in their classification depending on reaction to temperature, chemistry of synthesis and structure. Different polymers in different methods of manufacturing like bulk polymerization, solution polymerization, suspension polymerization and emulsion polymerization. Some polymers are completely eliminate from body with or without metabolism they are called as biodegradable polymer. Most of them shows issues of biocompatibility with tissues. Because of ease of manufacturing property of controlled drug release they are used in tablet coatings. Polyethylene, poly (ethylene-co-vinyl acetate) have widely use in ocuserts and progestarsarts. Hydrogels are kind of smart polymers which shows variation in properties in response to different environments. Most of the cancer therapies are based on polymer drug conjugates by binding polymers with a drug. Poly-ɛ-caprolactone, poly (lactate-co-glycolate) have importance in liposomes and nanosomal drug delivery systems. Polymers have recent application in progestarsarts, ocuserts, nanoparticles and swelling control release system.

Keywords: Biodegradable Polymers, Initiators, Hydrogels, Ocuserts, Monomer.