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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

MICROWAVE ASSISTED SYNTHESIS AND ANTI MICROBIAL ACTIVITY OF SOME NOVEL BENZTHIAZOLO PYRAZOLO QUINOXALINE COMPOUNDS

Tejasri Alla*, Swetha Naram Reddy, Kavya Esarapu, Jainendra Kumar Battineni, Vasudha Bakshi

ABSTRACT

A novel series of Benzthiazolo pyrazolo quinoxaline derivatives 6(a-e) have been synthesized and evaluated for anti-microbial activity by creating a new molecular frame work. Five new compounds were synthesized by treating chalcone 5(a-e), with benzoic acid hydrazide to yield Benzthiazolo pyrazolo quinoxaline compounds 6(a-e), by utilizing microwave energy. The structures of these newly synthesized compounds were confirmed by their spectral data and elemental analysis. These compounds have been screened for their anti-microbial activity. Towards all tested organisms compounds 6c, 6d and 6a give a significant anti bacterial activity, when compared with that of standard drug ampicillin. Also 6c, 6d and 6e compounds show moderate degree of anti fungal activity when compared with fluconazole.

Keywords: anti microbial activity, benzthiazolo pyrazolo quinoxaline erivatives, benzoic acid, fluconazole, chalcone.

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