Abstract

SIMULTANEOUS DETERMINATION OF BENZYL ALCOHOL AND IODIDE IN AMIODARONE HYDROCHLORIDE 150 mg/3mL INJECTION AT TWO DIFFERENT WAVELENGTHS WITH A SINGLE WAVELENGTH ABSORBANCE DETECTOR

*Tushar P. Ghule and Chandra B. Maurya

ABSTRACT

A precise and accurate chromatographic method has been developed by employing a mixed mode chromatographic column for simultaneous determination of Benzyl Alcohol (Organic analyte) and Iodide (Inorganic analyte) with appropriate sensitivity. The uniqueness of the method is that it enables measurement of both the analytes at two different wavelengths even with a single wavelength absorbance detector, in a single chromatographic run (as well as in a single chromatogram) without any conspicuous disturbance in the baseline.

Keywords: Benzyl Alcohol, Iodide, Amiodarone Hydrochloride 150 mg/3mL Injection.