Abstract

A REVIEW ON COMPUTER AIDED DRUG DESIGN IN DRUG DISCOVERY

Pratik Swarup Das* and Puja Saha

ABSTRACT

Computer aided drug design (CADD) is an evolving cascade of research area encompassing many facets. Computer-aided drug design (CADD) is an exciting and diverse discipline where various aspects of applied and basic research merge and stimulate each other. The theoretical basis of CADD involves quantum mechanics and molecular modeling studies like structure based drug design; ligand-based drug design; database searching and binding affinity based on the knowledge of a biological target.In this present review we present the areas where CADD tools support drug discovery process.

Keywords: Computer aided drug design, Molecular modeling, Biological target, Drug discovery process.