Abstract

A STUDY ON THE RESISTANCE PATTERN OF ANTIBIOTICS IN DIABETIC FOOT INFECTIONS IN A TERTIARY CARE HOSPITAL

S. Thangamani, Joseph R. Revathy*, Sabu P. Anumol, K. Anjali, S. A. Maisoon, Abdul Jaleel

ABSTRACT

Objective: To determine the resistance pattern of antibiotics against various clinical isolates in diabetic foot infections. Methodology: A prospective observational study was conducted for a period of 6 months in a tertiary care teaching hospital in Palakkad. Data regarding demographics and culture and sensitivity of the organisms in diabetic foot infection were collected. Results: The study showed a predominance of male gender(65.7%) and of the diabetic foot infections the most common infection was diabetic foot ulcer(55%) followed by cellulitis(34%) and gangrene(11%). Staphylococcus aureus was the most common pathogen isolated. Sensitivity testing showed that Cephalosporin were the most resistant antibiotic (57.6%) followed by Penicillin and others (42.3%). Conclusion: The degree of Cephalosporin resistance was found being increased alarmingly and this should be monitored since it may give rise to drug resistant diseases amplifying the use of other drugs.

Keywords: antibiotics, clinical isolates, resistance, Cephalosporin.