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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

A SIMPLIFIED CADOGEN’S APPROACH TO SYNTHESIS OF NEW THIOPHENYL AND PYRAZOLYL INDAZOLES

M. Prasada Reddy, Ravi Chandra Babu*, M. Sudhalakshmi and A. Siva Rami Reddy

ABSTRACT

Thiophene and pyrazol Schiff base have been prepared from the corresponding amines by reaction with 2-nitro benzaldehydes. These nitro compounds undergo de-oxygenative cyclization to give indazoles via nitrenes, on heating with triethylphosphite in acetonitrile. Thiophene and pyrazolyl indazoles have also been synthesized in a one pot reaction.

Keywords: Thiophene and pyrazolyl indazoles, one-pot synthesis, simplified cadogan's synthesis de-oxigenative cyclisation.

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