EVALUATION OF DIURETIC AND NEPHROPROTECTIVE ACTIVITY OF DESMOSTACHYA BIPINNATA IN ALBINO RATS
Azmath Farhana*, Swetha Naram Reddy, Teja Sri. A, Aliya Anjum and Vasudha Bakshi
ABSTRACT
Diuretic activity and nephroprotective activity of different extracts of
Desmostachya bipinnata in rat was studied. The study suggested that
the extracts have good diuretic property. Diuretic study was carried out
as per Lipschitz method. Where successive aquoeus, ethonolic and
petroleum extracts were studied for diuretic activity. The 6 hrs acute
study of successive aqueous, ethonolic extracts showed increase in
urine volume and K+ ion excretion as compared to control. However
advanced toxicological studies remain to be performed in rodents.
Extracts have shown moderate nephroprotective effect against
gentamicin induced nephrotoxicity.
Keywords: Desmostachya bipinnata, nephroprotectective action, lipschitz method.
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