WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

  • WJPPS: NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2024 Issue has been successfully launched on NOVEMBER 2024.

Abstract

SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUG ALBENDAZOLE BY SOLID DISPERSION TECHANIQUE

Harshada Patil*, Sulbha Patil and Dr. Sunil Pawar

ABSTRACT

This research work investigates enhancement of the solubility of albendazole by solid dispersion technique. A phase solubility study was used to evaluate the effect of various soluble polymers on aqueous solubility of Albendazole.The polymers used were Polyethylene glycol (PEG 6000), Hydroxy propyl methyl cellulose (HPMC E4) and solid dispersions were prepared by hot melt method and Kneding method. The prepared solid dispersions were characterized by Fourier transform spectroscopy (FTIR), to identify the physicochemical interaction between drug and polymers. The dissolution studies of solid dispersion were performed by using USP II apparatus (paddle type). Albendazole is a Anthelmintic drugnresistance has led to alternatives in controlling helminth infections.

Keywords: Solid dispersion, Albendazolel, HPMC E4, PEG6000 and Solubility enhancement.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More